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The Hematologic System ATI Pharmacology 4.0 Exam Questions with
Verified Answers 2023
1. A nurse should identify that clopidogrel is contraindicated for clients who have which of the
following conditions?
Answer: Peptic Ulcer Disease
2. A nurse is monitoring a client who is undergoing anticoagulant therapy with heparin. Which of
the following findings should nurse identify as a possible indication of hemorrhage?
Answer: Rapid Pulse
3. A nurse is caring for a client who is about to begin taking epoetin. An increase in which of the
following laboratory values should indicate to the nurse that the therapy is effective?
Answer: Hgb
4. A nurse is caring for a client who is taking clopidogrel to prevent stent restenosis. The nurse
should monitor the client for which of the following adverse reactions?
Answer: Thrombocytopenia
5. A nurse is caring for a client who has hemophilia A and is about to begin taking desmopressin
to prevent bleeding. The nurse should monitor the client for which of the following adverse
reactions?
Answer: Edema
6. A nurse is caring for a client who is about alteplase therapy to treat pulmonary embolism.
Which of the following drugs should the nurse have available in the event of a severe adverse
reaction?
Answer: Vitamin K
7. A nurse is caring for a client who is scheduled for an outpatient surgical procedure and reports
taking aspirin 81 mg daily, including this morning. The nurse should identify that this places the
client at risk for which of the following complications?
Answer: Uncontrolled bleeding
8. A nurse is caring for a client who recently started alteplase therapy. The nurse should monitor
the client for which of the following adverse effects?
Answer: Headache
9. A nurse is caring for a client who has renal failure and is receiving epoetin. The nurse should
monitor the client for which of the following adverse effects?
Answer: Hypertension
10. A nurse is teaching a client about taking ferrous sulfate to treat iron deficiency anemia.
Which of the following instructions should the nurse include?
Answer: • Eat iron-enriched foods
• Spread the dosage across each day
• Take the drug on an empty stomach
• Increase dietary fiber
11. A nurse is caring for a client who is taking ferrous sulfate to treat iron deficiency anemia and
develops toxicity. Which of the following drugs should the nurse expect to use to treat this
complication?
Answer: Deferoxamine
12. A nurse is caring for a client who is taking filgrastim to treat neutropenia. The nurse should
assess the client for which of the following adverse effects?
Answer: Enlarged Spleen
13. A nurse is caring for a client who has chronic stable angina. The nurse should identify that
which of the following drugs inhibits the actions of adenosine diphosphate receptors (ADP) on
platelets and can be prescribed to reduce the client's risk for myocardial infarction?
Answer: Clopidogrel
14. A nurse in an emergency department is assessing a client who has been taking warfarin and is
experiencing rectal bleeding. Which of the following drugs should the nurse expect to administer
to the client?
Answer: Vitamin K
15. A nurse is caring for a client who is about to begin taking aspirin to reduce the risk of a
cardiovascular event. The nurse should identify that the drug inhibits platelet aggregation by
which of the following mechanisms?
Answer: Inhibiting cyclooxygenase action in platelets
16. A nurse is monitoring a client following ferrous sulfate administration. The nurse should the
client for which of the following adverse effects?
Answer: Constipation
17. A nurse is teaching a client who is starting treatment with warfarin. The nurse should plan to
include information on which of the following topics to promote the effectiveness of the drug?
Answer: Dietary modifications
18. A nurse is reviewing the medication record of a client who is receiving alteplase following an
acute myocardial infarction (MI). Which of the following medications should the nurse expect
the client to be taking in addition to the alteplase?
Answer: Heparin
19. A nurse is caring for a client who is about to begin factor VIII therapy to treat hemophilia A.
When administering factor VIII, which of the following actions should the nurse take?
Answer: Have emergency equipment ready
20. A nurse is caring for a client who is experiencing an acute ischemic cerebrovascular event
due to thrombus in cerebral vessel. Which of the following drugs should the nurse expect to
administer?
Answer: Alteplase
21. A nurse is preparing to administer a prescribed dose of desmopressin to a client who has
hemophilia A. The client's laboratory results indicate that the client has a sodium level of 130
mEq/L. Which of the following actions should the nurse take?
Answer: Clarify the prescription with the provider
22. A nurse is caring for a client who is about to begin taking folic acid to treat megaloblastic
anemia. The nurse should monitor which of the following laboratory values to determine
therapeutic effectiveness?
Answer: Reticulocyte count
23. A nurse is caring for a client who is about to begin therapy with recombinant factor IX to
treat hemophilia B. The client asks the nurse about the risk of disease transmission with
recombinant factor IX as compared with plasma-derived factor IX. The nurse should explain that
recombinant factor IX therapy practically eliminates the risk for which of the following?
Answer: Creutzfeldt-Jakob disease
24. A nurse is administering epoetin intravenously to a client who has renal failure. Which of the
following actions should the nurse take?
Answer: Administer via IV bolus over 1 to 3 min
25. A nurse should assess a client who has megaloblastic anemia for indications of which of the
following vitamin deficiencies?
Answer: Vitamin B12
